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TPMT Activity ImmunoAssay
The patented Biologix TPMT Activity Assay is a competitive micro-well immunoassay for the semi-quantitative determination of TPMT activity in erythrocytes. TPMT catalyzes the S-methylation of 6-mercaptopurine (6-MP) with the presence of S-adenosylmethionine (SAM), the methyl donor, yielding 6-methylmercaptopurine (6-MMP). 6-MMP is then measured with a micro-well EIA. The level of patient TPMT activity level is the best indicator for individual patient's ability to metabolize certain medicines, avoid toxicities, and their individual therapeutic efficacy. These drugs are commonly used for the treatment of Inflammatory Bowel Diseases (IBDs), Leukemia, and many other medical conditions.
The successful development of specific antibodies against 6-MMP, a small molecule, and the introduction of the harsh methylation reaction product mix into the delicate immunoassay environment, mark a technological breakthrough.
This new assay system brings clinicians and patients tremendous benefits in the area of clinical pharmacogenomics, or in lay terms, Individualized Prescription.
NEW!
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Product Number
TPMT 150108
TPMT 150124
TPMT 150140
TPMT M40
Pack Insert
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Package Size
8 tests
24 tests
40 tests
40 tests
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