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TECHNOZYM® ADAMTS-13 ACTIVITY ELISA
Chromogenic ELISA for the determination of ADAMTS-13 activity in human plasma. ADAMTS-13 is an enzyme that specifically cleaves unusually large von Willebrand Factor multimers, which induce platelet thrombus formation under high shear stress. If the activity of ADAMTS-13 is lowered for some reason, unusually large vWF multimers may accumulate within blood causing thrombosis due to platelet aggregation, which in turn may lead to TTP (Thrombotic thrombocytopenic purpura).
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